Panama City

Direct return from Rio de Janeiro

£750 Save up to

£420 Best deal

£1170 Average cost

Panama City is a dynamic capital where the Panama Canal, a dramatic skyline, colonial streets, and tropical rainforest sit remarkably close together. Watch ships pass through the Miraflores Locks, wander the restored lanes of UNESCO-listed Casco Viejo, visit the ruins of Panamá Viejo, or spot wildlife in Metropolitan Natural Park just minutes from the city centre. With cosmopolitan restaurants, oceanfront promenades, and a strategic position between continents and oceans, Panama City feels like a true global crossroads.

Latest deals

5 days £420 Thu 29 Oct – Tue 3 Nov

Rio de Janeiro → Panama City · Thu 29/10 · £181 Go

Panama City → Rio de Janeiro · Tue 3/11 · £239 Go

11 days £420 Wed 28 Oct – Sun 8 Nov

Rio de Janeiro → Panama City · Wed 28/10 · £181 Go

Panama City → Rio de Janeiro · Sun 8/11 · £239 Go

12 days £420 Wed 28 Oct – Mon 9 Nov

Rio de Janeiro → Panama City · Wed 28/10 · £181 Go

Panama City → Rio de Janeiro · Mon 9/11 · £239 Go

13 days £420 Wed 28 Oct – Tue 10 Nov

Rio de Janeiro → Panama City · Wed 28/10 · £181 Go

Panama City → Rio de Janeiro · Tue 10/11 · £239 Go

6 days £420 Thu 29 Oct – Wed 4 Nov

Rio de Janeiro → Panama City · Thu 29/10 · £181 Go

Panama City → Rio de Janeiro · Wed 4/11 · £239 Go

7 days £420 Thu 29 Oct – Thu 5 Nov

Rio de Janeiro → Panama City · Thu 29/10 · £181 Go

Panama City → Rio de Janeiro · Thu 5/11 · £239 Go

8 days £420 Thu 29 Oct – Fri 6 Nov

Rio de Janeiro → Panama City · Thu 29/10 · £181 Go

Panama City → Rio de Janeiro · Fri 6/11 · £239 Go

9 days £420 Thu 29 Oct – Sat 7 Nov

Rio de Janeiro → Panama City · Thu 29/10 · £181 Go

Panama City → Rio de Janeiro · Sat 7/11 · £239 Go

10 days £420 Thu 29 Oct – Sun 8 Nov

Rio de Janeiro → Panama City · Thu 29/10 · £181 Go

Panama City → Rio de Janeiro · Sun 8/11 · £239 Go

11 days £420 Thu 29 Oct – Mon 9 Nov

Rio de Janeiro → Panama City · Thu 29/10 · £181 Go

Panama City → Rio de Janeiro · Mon 9/11 · £239 Go

12 days £420 Thu 29 Oct – Tue 10 Nov

Rio de Janeiro → Panama City · Thu 29/10 · £181 Go

Panama City → Rio de Janeiro · Tue 10/11 · £239 Go

6 days £420 Fri 30 Oct – Thu 5 Nov

Rio de Janeiro → Panama City · Fri 30/10 · £181 Go

Panama City → Rio de Janeiro · Thu 5/11 · £239 Go

7 days £420 Fri 30 Oct – Fri 6 Nov

Rio de Janeiro → Panama City · Fri 30/10 · £181 Go

Panama City → Rio de Janeiro · Fri 6/11 · £239 Go

8 days £420 Fri 30 Oct – Sat 7 Nov

Rio de Janeiro → Panama City · Fri 30/10 · £181 Go

Panama City → Rio de Janeiro · Sat 7/11 · £239 Go

9 days £420 Fri 30 Oct – Sun 8 Nov

Rio de Janeiro → Panama City · Fri 30/10 · £181 Go

Panama City → Rio de Janeiro · Sun 8/11 · £239 Go

10 days £420 Fri 30 Oct – Mon 9 Nov

Rio de Janeiro → Panama City · Fri 30/10 · £181 Go

Panama City → Rio de Janeiro · Mon 9/11 · £239 Go

11 days £420 Fri 30 Oct – Tue 10 Nov

Rio de Janeiro → Panama City · Fri 30/10 · £181 Go

Panama City → Rio de Janeiro · Tue 10/11 · £239 Go

6 days £420 Sat 31 Oct – Fri 6 Nov

Rio de Janeiro → Panama City · Sat 31/10 · £181 Go

Panama City → Rio de Janeiro · Fri 6/11 · £239 Go

7 days £420 Sat 31 Oct – Sat 7 Nov

Rio de Janeiro → Panama City · Sat 31/10 · £181 Go

Panama City → Rio de Janeiro · Sat 7/11 · £239 Go

8 days £420 Sat 31 Oct – Sun 8 Nov

Rio de Janeiro → Panama City · Sat 31/10 · £181 Go

Panama City → Rio de Janeiro · Sun 8/11 · £239 Go

9 days £420 Sat 31 Oct – Mon 9 Nov

Rio de Janeiro → Panama City · Sat 31/10 · £181 Go

Panama City → Rio de Janeiro · Mon 9/11 · £239 Go

10 days £420 Sat 31 Oct – Tue 10 Nov

Rio de Janeiro → Panama City · Sat 31/10 · £181 Go

Panama City → Rio de Janeiro · Tue 10/11 · £239 Go

6 days £420 Sun 1 Nov – Sat 7 Nov

Rio de Janeiro → Panama City · Sun 1/11 · £181 Go

Panama City → Rio de Janeiro · Sat 7/11 · £239 Go

7 days £420 Sun 1 Nov – Sun 8 Nov

Rio de Janeiro → Panama City · Sun 1/11 · £181 Go

Panama City → Rio de Janeiro · Sun 8/11 · £239 Go

8 days £420 Sun 1 Nov – Mon 9 Nov

Rio de Janeiro → Panama City · Sun 1/11 · £181 Go

Panama City → Rio de Janeiro · Mon 9/11 · £239 Go

9 days £420 Sun 1 Nov – Tue 10 Nov

Rio de Janeiro → Panama City · Sun 1/11 · £181 Go

Panama City → Rio de Janeiro · Tue 10/11 · £239 Go

6 days £420 Mon 2 Nov – Sun 8 Nov

Rio de Janeiro → Panama City · Mon 2/11 · £181 Go

Panama City → Rio de Janeiro · Sun 8/11 · £239 Go

7 days £420 Mon 2 Nov – Mon 9 Nov

Rio de Janeiro → Panama City · Mon 2/11 · £181 Go

Panama City → Rio de Janeiro · Mon 9/11 · £239 Go

8 days £420 Mon 2 Nov – Tue 10 Nov

Rio de Janeiro → Panama City · Mon 2/11 · £181 Go

Panama City → Rio de Janeiro · Tue 10/11 · £239 Go

6 days £420 Tue 3 Nov – Mon 9 Nov

Rio de Janeiro → Panama City · Tue 3/11 · £181 Go

Panama City → Rio de Janeiro · Mon 9/11 · £239 Go

10 days £420 Wed 28 Oct – Sat 7 Nov

Rio de Janeiro → Panama City · Wed 28/10 · £181 Go

Panama City → Rio de Janeiro · Sat 7/11 · £239 Go

9 days £420 Wed 28 Oct – Fri 6 Nov

Rio de Janeiro → Panama City · Wed 28/10 · £181 Go

Panama City → Rio de Janeiro · Fri 6/11 · £239 Go

8 days £420 Wed 28 Oct – Thu 5 Nov

Rio de Janeiro → Panama City · Wed 28/10 · £181 Go

Panama City → Rio de Janeiro · Thu 5/11 · £239 Go

7 days £420 Wed 28 Oct – Wed 4 Nov

Rio de Janeiro → Panama City · Wed 28/10 · £181 Go

Panama City → Rio de Janeiro · Wed 4/11 · £239 Go

4 days £420 Fri 30 Oct – Tue 3 Nov

Rio de Janeiro → Panama City · Fri 30/10 · £181 Go

Panama City → Rio de Janeiro · Tue 3/11 · £239 Go

5 days £420 Fri 30 Oct – Wed 4 Nov

Rio de Janeiro → Panama City · Fri 30/10 · £181 Go

Panama City → Rio de Janeiro · Wed 4/11 · £239 Go

3 days £420 Sat 31 Oct – Tue 3 Nov

Rio de Janeiro → Panama City · Sat 31/10 · £181 Go

Panama City → Rio de Janeiro · Tue 3/11 · £239 Go

4 days £420 Sat 31 Oct – Wed 4 Nov

Rio de Janeiro → Panama City · Sat 31/10 · £181 Go

Panama City → Rio de Janeiro · Wed 4/11 · £239 Go

5 days £420 Sat 31 Oct – Thu 5 Nov

Rio de Janeiro → Panama City · Sat 31/10 · £181 Go

Panama City → Rio de Janeiro · Thu 5/11 · £239 Go

2 days £420 Sun 1 Nov – Tue 3 Nov

Rio de Janeiro → Panama City · Sun 1/11 · £181 Go

Panama City → Rio de Janeiro · Tue 3/11 · £239 Go

3 days £420 Sun 1 Nov – Wed 4 Nov

Rio de Janeiro → Panama City · Sun 1/11 · £181 Go

Panama City → Rio de Janeiro · Wed 4/11 · £239 Go

4 days £420 Sun 1 Nov – Thu 5 Nov

Rio de Janeiro → Panama City · Sun 1/11 · £181 Go

Panama City → Rio de Janeiro · Thu 5/11 · £239 Go

5 days £420 Sun 1 Nov – Fri 6 Nov

Rio de Janeiro → Panama City · Sun 1/11 · £181 Go

Panama City → Rio de Janeiro · Fri 6/11 · £239 Go

2 days £420 Mon 2 Nov – Wed 4 Nov

Rio de Janeiro → Panama City · Mon 2/11 · £181 Go

Panama City → Rio de Janeiro · Wed 4/11 · £239 Go

3 days £420 Mon 2 Nov – Thu 5 Nov

Rio de Janeiro → Panama City · Mon 2/11 · £181 Go

Panama City → Rio de Janeiro · Thu 5/11 · £239 Go

4 days £420 Mon 2 Nov – Fri 6 Nov

Rio de Janeiro → Panama City · Mon 2/11 · £181 Go

Panama City → Rio de Janeiro · Fri 6/11 · £239 Go

5 days £420 Mon 2 Nov – Sat 7 Nov

Rio de Janeiro → Panama City · Mon 2/11 · £181 Go

Panama City → Rio de Janeiro · Sat 7/11 · £239 Go

2 days £420 Tue 3 Nov – Thu 5 Nov

Rio de Janeiro → Panama City · Tue 3/11 · £181 Go

Panama City → Rio de Janeiro · Thu 5/11 · £239 Go

7 days £420 Tue 3 Nov – Tue 10 Nov

Rio de Janeiro → Panama City · Tue 3/11 · £181 Go

Panama City → Rio de Janeiro · Tue 10/11 · £239 Go

3 days £420 Tue 3 Nov – Fri 6 Nov

Rio de Janeiro → Panama City · Tue 3/11 · £181 Go

Panama City → Rio de Janeiro · Fri 6/11 · £239 Go

... 16 more possible dates exist ...