Panama City

Direct return from Sao Paulo

£758 Save up to

£383 Best deal

£1141 Average cost

Panama City is a dynamic capital where the Panama Canal, a dramatic skyline, colonial streets, and tropical rainforest sit remarkably close together. Watch ships pass through the Miraflores Locks, wander the restored lanes of UNESCO-listed Casco Viejo, visit the ruins of Panamá Viejo, or spot wildlife in Metropolitan Natural Park just minutes from the city centre. With cosmopolitan restaurants, oceanfront promenades, and a strategic position between continents and oceans, Panama City feels like a true global crossroads.

Latest deals

5 days £383 Thu 29 Oct – Tue 3 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Tue 3/11 · £205 Go

7 days £383 Sat 31 Oct – Sat 7 Nov

Sao Paulo → Panama City · Sat 31/10 · £178 Go

Panama City → Sao Paulo · Sat 7/11 · £205 Go

6 days £383 Sat 31 Oct – Fri 6 Nov

Sao Paulo → Panama City · Sat 31/10 · £178 Go

Panama City → Sao Paulo · Fri 6/11 · £205 Go

13 days £383 Fri 30 Oct – Thu 12 Nov

Sao Paulo → Panama City · Fri 30/10 · £178 Go

Panama City → Sao Paulo · Thu 12/11 · £205 Go

12 days £383 Fri 30 Oct – Wed 11 Nov

Sao Paulo → Panama City · Fri 30/10 · £178 Go

Panama City → Sao Paulo · Wed 11/11 · £205 Go

11 days £383 Fri 30 Oct – Tue 10 Nov

Sao Paulo → Panama City · Fri 30/10 · £178 Go

Panama City → Sao Paulo · Tue 10/11 · £205 Go

10 days £383 Fri 30 Oct – Mon 9 Nov

Sao Paulo → Panama City · Fri 30/10 · £178 Go

Panama City → Sao Paulo · Mon 9/11 · £205 Go

9 days £383 Fri 30 Oct – Sun 8 Nov

Sao Paulo → Panama City · Fri 30/10 · £178 Go

Panama City → Sao Paulo · Sun 8/11 · £205 Go

8 days £383 Fri 30 Oct – Sat 7 Nov

Sao Paulo → Panama City · Fri 30/10 · £178 Go

Panama City → Sao Paulo · Sat 7/11 · £205 Go

7 days £383 Fri 30 Oct – Fri 6 Nov

Sao Paulo → Panama City · Fri 30/10 · £178 Go

Panama City → Sao Paulo · Fri 6/11 · £205 Go

6 days £383 Fri 30 Oct – Thu 5 Nov

Sao Paulo → Panama City · Fri 30/10 · £178 Go

Panama City → Sao Paulo · Thu 5/11 · £205 Go

14 days £383 Thu 29 Oct – Thu 12 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Thu 12/11 · £205 Go

13 days £383 Thu 29 Oct – Wed 11 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Wed 11/11 · £205 Go

12 days £383 Thu 29 Oct – Tue 10 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Tue 10/11 · £205 Go

11 days £383 Thu 29 Oct – Mon 9 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Mon 9/11 · £205 Go

10 days £383 Thu 29 Oct – Sun 8 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Sun 8/11 · £205 Go

9 days £383 Thu 29 Oct – Sat 7 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Sat 7/11 · £205 Go

8 days £383 Thu 29 Oct – Fri 6 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Fri 6/11 · £205 Go

8 days £383 Sat 31 Oct – Sun 8 Nov

Sao Paulo → Panama City · Sat 31/10 · £178 Go

Panama City → Sao Paulo · Sun 8/11 · £205 Go

7 days £383 Thu 29 Oct – Thu 5 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Thu 5/11 · £205 Go

9 days £383 Sat 31 Oct – Mon 9 Nov

Sao Paulo → Panama City · Sat 31/10 · £178 Go

Panama City → Sao Paulo · Mon 9/11 · £205 Go

11 days £383 Sat 31 Oct – Wed 11 Nov

Sao Paulo → Panama City · Sat 31/10 · £178 Go

Panama City → Sao Paulo · Wed 11/11 · £205 Go

6 days £383 Wed 4 Nov – Tue 10 Nov

Sao Paulo → Panama City · Wed 4/11 · £178 Go

Panama City → Sao Paulo · Tue 10/11 · £205 Go

9 days £383 Tue 3 Nov – Thu 12 Nov

Sao Paulo → Panama City · Tue 3/11 · £178 Go

Panama City → Sao Paulo · Thu 12/11 · £205 Go

8 days £383 Tue 3 Nov – Wed 11 Nov

Sao Paulo → Panama City · Tue 3/11 · £178 Go

Panama City → Sao Paulo · Wed 11/11 · £205 Go

7 days £383 Tue 3 Nov – Tue 10 Nov

Sao Paulo → Panama City · Tue 3/11 · £178 Go

Panama City → Sao Paulo · Tue 10/11 · £205 Go

6 days £383 Tue 3 Nov – Mon 9 Nov

Sao Paulo → Panama City · Tue 3/11 · £178 Go

Panama City → Sao Paulo · Mon 9/11 · £205 Go

10 days £383 Mon 2 Nov – Thu 12 Nov

Sao Paulo → Panama City · Mon 2/11 · £178 Go

Panama City → Sao Paulo · Thu 12/11 · £205 Go

9 days £383 Mon 2 Nov – Wed 11 Nov

Sao Paulo → Panama City · Mon 2/11 · £178 Go

Panama City → Sao Paulo · Wed 11/11 · £205 Go

8 days £383 Mon 2 Nov – Tue 10 Nov

Sao Paulo → Panama City · Mon 2/11 · £178 Go

Panama City → Sao Paulo · Tue 10/11 · £205 Go

7 days £383 Mon 2 Nov – Mon 9 Nov

Sao Paulo → Panama City · Mon 2/11 · £178 Go

Panama City → Sao Paulo · Mon 9/11 · £205 Go

6 days £383 Mon 2 Nov – Sun 8 Nov

Sao Paulo → Panama City · Mon 2/11 · £178 Go

Panama City → Sao Paulo · Sun 8/11 · £205 Go

11 days £383 Sun 1 Nov – Thu 12 Nov

Sao Paulo → Panama City · Sun 1/11 · £178 Go

Panama City → Sao Paulo · Thu 12/11 · £205 Go

10 days £383 Sun 1 Nov – Wed 11 Nov

Sao Paulo → Panama City · Sun 1/11 · £178 Go

Panama City → Sao Paulo · Wed 11/11 · £205 Go

9 days £383 Sun 1 Nov – Tue 10 Nov

Sao Paulo → Panama City · Sun 1/11 · £178 Go

Panama City → Sao Paulo · Tue 10/11 · £205 Go

8 days £383 Sun 1 Nov – Mon 9 Nov

Sao Paulo → Panama City · Sun 1/11 · £178 Go

Panama City → Sao Paulo · Mon 9/11 · £205 Go

7 days £383 Sun 1 Nov – Sun 8 Nov

Sao Paulo → Panama City · Sun 1/11 · £178 Go

Panama City → Sao Paulo · Sun 8/11 · £205 Go

6 days £383 Sun 1 Nov – Sat 7 Nov

Sao Paulo → Panama City · Sun 1/11 · £178 Go

Panama City → Sao Paulo · Sat 7/11 · £205 Go

12 days £383 Sat 31 Oct – Thu 12 Nov

Sao Paulo → Panama City · Sat 31/10 · £178 Go

Panama City → Sao Paulo · Thu 12/11 · £205 Go

10 days £383 Sat 31 Oct – Tue 10 Nov

Sao Paulo → Panama City · Sat 31/10 · £178 Go

Panama City → Sao Paulo · Tue 10/11 · £205 Go

6 days £383 Thu 29 Oct – Wed 4 Nov

Sao Paulo → Panama City · Thu 29/10 · £178 Go

Panama City → Sao Paulo · Wed 4/11 · £205 Go

15 days £383 Wed 28 Oct – Thu 12 Nov

Sao Paulo → Panama City · Wed 28/10 · £178 Go

Panama City → Sao Paulo · Thu 12/11 · £205 Go

14 days £383 Wed 28 Oct – Wed 11 Nov

Sao Paulo → Panama City · Wed 28/10 · £178 Go

Panama City → Sao Paulo · Wed 11/11 · £205 Go

5 days £383 Tue 3 Nov – Sun 8 Nov

Sao Paulo → Panama City · Tue 3/11 · £178 Go

Panama City → Sao Paulo · Sun 8/11 · £205 Go

4 days £383 Tue 3 Nov – Sat 7 Nov

Sao Paulo → Panama City · Tue 3/11 · £178 Go

Panama City → Sao Paulo · Sat 7/11 · £205 Go

3 days £383 Tue 3 Nov – Fri 6 Nov

Sao Paulo → Panama City · Tue 3/11 · £178 Go

Panama City → Sao Paulo · Fri 6/11 · £205 Go

2 days £383 Tue 3 Nov – Thu 5 Nov

Sao Paulo → Panama City · Tue 3/11 · £178 Go

Panama City → Sao Paulo · Thu 5/11 · £205 Go

5 days £383 Mon 2 Nov – Sat 7 Nov

Sao Paulo → Panama City · Mon 2/11 · £178 Go

Panama City → Sao Paulo · Sat 7/11 · £205 Go

4 days £383 Mon 2 Nov – Fri 6 Nov

Sao Paulo → Panama City · Mon 2/11 · £178 Go

Panama City → Sao Paulo · Fri 6/11 · £205 Go

3 days £383 Mon 2 Nov – Thu 5 Nov

Sao Paulo → Panama City · Mon 2/11 · £178 Go

Panama City → Sao Paulo · Thu 5/11 · £205 Go

... 34 more possible dates exist ...